In seizoen één van The Second Best Hospital in the Galaxy krijgen Sleech en Klak een gevaarlijke en mogelijk baanbrekende zaak en zo het bestaan zelf in gevaar brengen. Hoewel met hun verschrikkelijke persoonlijke leven de vergetelheid misschien een verbetering is.
 | Seizoen 1 Aflevering 1 Sometimes Heads Break Datum: 2024-02-23 Lengte: 28 min |
 | Seizoen 1 Aflevering 2 The Land of Sex and Death Datum: 2024-02-23 Lengte: 23 min |
 | Seizoen 1 Aflevering 3 Tomorrow’s Death is Yesterday’s Problem Datum: 2024-02-23 Lengte: 24 min |
 | Seizoen 1 Aflevering 4 The Curse of Orlosh Datum: 2024-02-23 Lengte: 28 min |
 | Seizoen 1 Aflevering 5 Beef Sturgeon Sleech Datum: 2024-02-23 Lengte: 25 min |
 | Seizoen 1 Aflevering 6 That’s Science, Baby! Datum: 2024-02-23 Lengte: 27 min |
 | Seizoen 1 Aflevering 7 Just One More Adjustment Datum: 2024-02-23 Lengte: 26 min |
 | Seizoen 1 Aflevering 8 Apocalypse Got You Down? Datum: 2024-02-23 Lengte: 24 min |
| Production | Maya Rudolph | Executive Producer |
| Production | Natasha Lyonne | Executive Producer |
| Production | Danielle Renfrew Behrens | Executive Producer |
| Production | Shauna McGarry | Executive Producer |
| Production | Cirocco Dunlap | Executive Producer |
| Production | Robin Eisenberg | Co-Producer |
| Production | Shannon Prynoski | Executive Producer |
| Production | Chris Prynoski | Executive Producer |
| Production | Antonio Canobbio | Executive Producer |
| Production | Ben Kalina | Executive Producer |
| Art | Robin Eisenberg | Production Design |
| Production | Anne Lane | Supervising Producer |
| Production | Jennifer Ray | Supervising Producer |
| Production | Asha Michelle Wilson | Producer |
| Production | Whitney Loveall | Producer |
| Writing | Joanna Bradley | Story Editor |
| Writing | Kirsten King | Staff Writer |
| Art | Tyler Rice | Art Direction |
| Visual Effects | Robin Eisenberg | Character Designer |
| Sound | Wendy Melvoin | Original Music Composer |
| Sound | Lisa Coleman | Original Music Composer |
| Production | Julie Ashton | Casting Director |
| Production | Joey Cee | Casting Associate |
| Production | Kristi Reed | Other |
| Production | Ashley Nguyen DeWitt | Other |
| Editing | Cassandra Hanks | Assistant Editor |
| Sound | Ian Logan | Dialogue Editor |
| Visual Effects | Marika Cowan | Lead Character Designer |
| Art | Erik Caines | Background Designer |
| Art | Mariana Vasconcelos | Other |
| Production | Ramon Vasconcelos | Line Producer |
| Production | Alexandrina Santos | Line Producer |
| Production | Andre Barroso | Line Producer |
| Visual Effects | Edilson Alves | Animation Supervisor |
| Visual Effects | Rodrigo Frias | Animation Supervisor |
| Lighting | Odemilson Sconieczni | Rigging Supervisor |
| Production | Pam Hauber | Production Coordinator |
| Production | Laura Senna | Production Supervisor |
| Art | Zé Brandão | Creative Director |
| Production | Glaucea Rodrigues | Finance |
| Production | Vivian Amadio | Head of Production |
| Production | Rhobyn de Jesus | Production Manager |
| Production | Nick Monteleone | Production Manager |
| Directing | Cooper Villalon Nelson | Script Coordinator |
| Directing | Johanna Ramm | Script Coordinator |
| Writing | Erika Vázquez | Writers' Assistant |
| Production | Samantha Afable | Production Coordinator |
| Production | Armando H. Chavira | Production Coordinator |
| Production | Alistair Leo Rice | Production Coordinator |
| Production | Areyon Jolivette | Executive Assistant |
| Production | Ben Poppleton | Executive Assistant |
| Production | Tara Riedl | Executive Assistant |
| Sound | Paul Hurtubise | Sound Re-Recording Mixer |
| Sound | Tiffany Anders | Music Supervisor |
| Sound | James Lucero | Supervising Sound Editor |
| Sound | Jenny Barak | Music Editor |
| Sound | John Wynn | Sound Effects Editor |
| Sound | Makenzie Kellerman | Sound Effects Editor |
| Sound | T.C. Spriggs | Sound Effects Editor |
| Sound | Amber D. Bruce | Foley Editor |
| Sound | Michael Britt | Foley Editor |
| Sound | Drew Guy | Other |
| Production | Christina Chavarria | Production Accountant |
