In 1985 wenst de achtjarige John Bennett zijn teddybeer tot leven. Ze groeien samen op en Ted wordt wereldberoemd. Jaren later, in 1993, staat de bijdehante en grofgebekte teddybeer niet meer in de schijnwerpers. Ted woont nu weer thuis in Framingham, Massachusetts met zijn beste vriend, een inmiddels zestienjarige John, diens ouders Matty en Susan en nicht Blaire. Misschien heeft Ted een slechte invloed op John, maar uiteindelijk is hij een trouwe vriend die altijd bereid is om zijn nek uit te steken voor vriendschap.
 | Seizoen 1 Aflevering 1 Just Say Yes Datum: 2024-01-11 Lengte: 51 min |
 | Seizoen 1 Aflevering 2 My Two Dads Datum: 2024-01-11 Lengte: 39 min |
 | Seizoen 1 Aflevering 3 Ejectile Dysfunction Datum: 2024-01-11 Lengte: 37 min |
 | Seizoen 1 Aflevering 4 Subways, Bicycles, and Automobiles Datum: 2024-01-11 Lengte: 37 min |
 | Seizoen 1 Aflevering 5 Desperately Seeking Susan Datum: 2024-01-11 Lengte: 34 min |
 | Seizoen 1 Aflevering 6 Loud Night Datum: 2024-01-11 Lengte: 44 min |
 | Seizoen 1 Aflevering 7 He's Gotta Have It Datum: 2024-01-11 Lengte: 43 min |
| Production | Seth MacFarlane | Executive Producer |
| Production | Paul Corrigan | Executive Producer |
| Production | Jason Clark | Executive Producer |
| Production | Erica Huggins | Executive Producer |
| Production | Brad Walsh | Executive Producer |
| Production | Alana Kleiman | Executive Producer |
| Production | Chelsea Davison | Supervising Producer |
| Sound | Walter Murphy | Original Music Composer |
| Sound | Walter Murphy | Main Title Theme Composer |
| Sound | Seth MacFarlane | Main Title Theme Composer |
| Sound | Norah Jones | Theme Song Performance |
| Production | John Jacobs | Producer |
| Camera | Jeffrey C. Mygatt | Director of Photography |
| Production | Gail Goldberg | Casting |
| Production | Sheila Jaffe | Casting |
| Art | Stephen J. Lineweaver | Production Design |
| Costume & Make-Up | Heather Pain | Costume Design |
| Sound | Tom Ozanich | Sound Re-Recording Mixer |
| Sound | Ron Mellegers | Foley Mixer |
| Sound | Mike McKone | Sound Effects Editor |
| Sound | Joshua Anderson | Production Sound Mixer |
| Visual Effects | Glenn Melenhorst | Visual Effects Supervisor |
| Visual Effects | Ineke Majoor | Visual Effects Producer |
| Visual Effects | Dennis Hoffman | Visual Effects Producer |
| Visual Effects | Blair Clark | Visual Effects Supervisor |
| Visual Effects | Paul Boyd | VFX Artist |
| Production | Alexis Winter | Casting Associate |
| Sound | Seth MacFarlane | Songs |
| Production | Alex John Wiseman | Co-Producer |
| Production | Tom Costantino | Co-Producer |
| Production | Dana Gould | Consulting Producer |
| Production | Aaron Lee | Consulting Producer |
| Production | Patrick Meighan | Consulting Producer |
| Production | Alec Sulkin | Consulting Producer |
| Production | John Viener | Consulting Producer |
| Writing | Charlene deGuzman | Staff Writer |
| Writing | Charlie Hankin | Staff Writer |
| Writing | Hannah Murphy | Staff Writer |
| Writing | Matt Porter | Staff Writer |
| Production | Lillian Awa | Unit Production Manager |
| Directing | Mikaela Mathern | Second Assistant Director |
| Camera | Bill Brummond | Camera Operator |
| Camera | Toby Tucker | Camera Operator |
| Lighting | Stephan Dalyai | Chief Lighting Technician |
| Camera | Stuart Abramson | Key Grip |
| Camera | Drew Abramson | Best Boy Grip |
| Art | Robert Strohmaier | Art Direction |
| Art | Ellen Totleben | Set Decoration |
| Art | Daniel Saks | Set Designer |
| Art | Rich Rohrer | Set Designer |
| Art | John Harrington | Property Master |
| Directing | Tim Wrobel | Script Supervisor |
| Costume & Make-Up | Audrey Futterman-Stern | Hair Department Head |
| Costume & Make-Up | Kimberly Greene | Makeup Department Head |
| Costume & Make-Up | Kc Mussman | Key Makeup Artist |
| Costume & Make-Up | Jennifer Ashley Connell | Key Costumer |
| Costume & Make-Up | Mischa Fruge | Key Hair Stylist |
| Sound | Jon Greasley | Supervising Sound Editor |
| Sound | Jon Greasley | Sound Re-Recording Mixer |
| Sound | John-Thomas Graves | Supervising Dialogue Editor |
| Sound | John-Thomas Graves | ADR Editor |
| Sound | Mike McKone | Sound Designer |
| Sound | Shawn Murphy | Scoring Mixer |
| Production | Joy Fehily | Co-Executive Producer |
