Een Amerikaanse satelliet stort neer in de buurt van een klein stadje in Utah, waardoor een dodelijke plaag ontstaat die vrijwel iedereen doodt, behalve twee overlevenden, die aanwijzingen kunnen geven voor het immuniseren van de bevolking. Terwijl het leger probeert het gebied in quarantaine te plaatsen, wordt een team van zeer gespecialiseerde wetenschappers samengesteld om een geneesmiddel te vinden en de verspreiding van de buitenaardse ziekteverwekker, met de codenaam Andromeda, te stoppen.
 | Seizoen 1 Aflevering 1 Part 1 Datum: 2008-05-26 Lengte: 120 min |
 | Seizoen 1 Aflevering 2 Part 2 Datum: 2008-05-27 Lengte: 120 min |
| Production | Tony Scott | Executive Producer |
| Production | Ridley Scott | Executive Producer |
| Production | David W. Zucker | Executive Producer |
| Production | Tom Thayer | Executive Producer |
| Production | Mikael Salomon | Producer |
| Production | Clara George | Producer |
| Camera | Jon Joffin | Director of Photography |
| Editing | Scott Vickrey | Editor |
| Production | Denise Chamian | Casting |
| Production | Scout Masterson | Casting |
| Art | Jerry Wanek | Production Design |
| Art | Dan Hermansen | Art Direction |
| Art | Merlin Dervisevic | Set Decoration |
| Costume & Make-Up | Jenni Gullett | Costume Design |
| Directing | Crystal Braunwarth | Script Coordinator |
| Directing | Patti Henderson | Script Supervisor |
| Production | Ron Binkowski | Co-Producer |
| Production | Malcolm Reeve | Co-Producer |
| Costume & Make-Up | Jill Bailey | Makeup Artist |
| Costume & Make-Up | Ian C. Ballard | Key Hair Stylist |
| Costume & Make-Up | Susan Boyd | Hairstylist |
| Costume & Make-Up | Connie Parker | Makeup Department Head |
| Crew | Nicholas Podbrey | Makeup Effects |
| Production | Julia Neville | Production Manager |
| Directing | Ken Shane | First Assistant Director |
| Art | Josephine Bleuer | Greensman |
| Art | Dean Eilertson | Property Master |
| Art | Roger Jacoe | Lead Painter |
| Art | Vicky Peters | Set Designer |
| Art | Glenn Woodruff | Construction Coordinator |
| Art | Adrian Hrytzak | Art Department Coordinator |
| Sound | Bill Bell | Sound Editor |
| Sound | Bob Costanza | Sound Editor |
| Sound | Mike Dickeson | Sound Editor |
| Sound | Erich Gann | Sound Effects Editor |
| Sound | G. Michael Graham | Supervising Sound Editor |
| Sound | Devon Heffley Curry | Supervising ADR Editor |
| Sound | Anton Holden | Sound Editor |
| Sound | Robert McDonagh | Boom Operator |
| Sound | Terry O'Bright | Sound Re-Recording Mixer |
| Sound | Keith Rogers | Sound Re-Recording Mixer |
| Sound | Richard Steele | Sound Designer |
| Sound | Tim Terusa | Sound Editor |
| Sound | Daniel Tripoli | Sound Editor |
| Crew | Tony Lazarowich | Special Effects Coordinator |
| Visual Effects | Jan Vseticek | Visual Effects Coordinator |
| Visual Effects | David Vána | Visual Effects Supervisor |
| Crew | Dave Hospes | Stunt Coordinator |
| Camera | Jim Filippone | Helicopter Camera |
| Camera | Russell Hawkes | Dolly Grip |
| Camera | Simon Jori | First Assistant Camera |
| Lighting | Mike Kolafa | Gaffer |
| Camera | John Kuchera | Key Grip |
| Camera | Marty McInally | Camera Operator |
| Camera | Ryan Monro | Dolly Grip |
| Camera | Pascal Jean Provost | Camera Operator |
| Lighting | Keith Woods | Rigging Gaffer |
| Costume & Make-Up | Paul Lavigne | Wardrobe Supervisor |
| Costume & Make-Up | Karin Nosella | Costume Coordinator |
| Editing | Josh Beal | Assistant Editor |
| Editing | Jessica Schulte | Assistant Editor |
| Production | Bruce L. Brownstein | Location Manager |
| Sound | Bunny Andrews | Music Editor |
| Production | Adrienne Sol | Production Coordinator |
| Crew | Ryan Steacy | Armorer |
| Sound | Joel J. Richard | Original Music Composer |
| Crew | Doug Chapman | Stunts |
| Writing | Michael Crichton | Novel |
| Writing | Robert Schenkkan | Screenplay |
